Prognostic factors versus predictive factors: Examples from a clinical trial of erlotinib
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چکیده
منابع مشابه
Prognostic and predictive factors.
Prognostic factors are key elements for medical oncologists to select, among the group of patients with early breast cancer, those who are candidates for an adjuvant treatment based on their risk of tumor relapse. Predictive factors drive the decision of which type(s) of treatment should be given. If we perform a literature search on prognostic and predictive factors in breast cancer we immedia...
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Prognostication of newly diagnosed colorectal cancer (CRC) predominantly relies on stage as defined by the UICC-TNM and American Joint Committee on Cancer classifications. Tumour extent, lymph node status, tumour grade and the assessment of lymphatic and venous invasion are still the most important morphological prognostic factors. Evidence suggests that tumour budding and tumour border configu...
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It is an exciting time for all those engaged in the treatment of colorectal cancer. The advent of new therapies presents the opportunity for a personalized approach to the patient. This approach considers the complex genetic mechanisms involved in tumorigenesis in addition to classical clinicopathological staging. The potential predictive and prognostic biomarkers which have stemmed from the st...
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Oral squamous cell carcinoma has a remarkable incidence worldwide and a fairly onerous prognosis, encouraging further research on factors that might modify disease outcome. In this review article, the authors approach the factors that may exert influence on the prognosis and eventually guide the selection of patients for more aggressive therapies. Published scientific data was collected, select...
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Background: Controlled ovarian hyper stimulation (COH) in conjunction with intrauterine insemination (IUI) is frequently used to treat various causes of infertility in couples. In this study we evaluate the relation between IUI outcomes and infertility with the intent to detect the most important parameters that pertain to a successful IUI. Materials and Methods: In this cross-sectional study, ...
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ژورنال
عنوان ژورنال: Molecular Oncology
سال: 2007
ISSN: 1574-7891
DOI: 10.1016/j.molonc.2007.12.001